Reagent for coagulating blood

Details Reagent for coagulating blood Reagent for coagulating blood

1993-11-18

1995-03-28

Warden, Robert J.

Chemistry: analytical and immunological testing

Clotting or clotting factor level tests

436 16, 436 18, 436 71, 435 2, 435 13, 435214, 2524081, 530381, 530382, 530384, G01N 3386

Patent

active

054016630

ABSTRACT:
A reagent blood coagulation that causes an increase in turbidity changes when added to a plasma sample containing a substance activating coagulation factor activating such as tissue thromboplastin, phospholipid and thrombin, calcium ion, and molecular substance such as high molecular vinyl and a high molecular polysaccharide. By adding a molecular substance to the reagent, the turbidity change due to blood coagulation is increased, and hence the changing quantity of transmitted light or scattered light increases, thereby making it possible to achieve a more accurate detection. Besides, by adjusting the electric conductivity, pH and osmotic pressure to proper values, the turbidity change due to blood coagulation may be further amplified.

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