Bis (hydroxymethyl) cyclobutyl purines

Details Bis (hydroxymethyl) cyclobutyl purines Bis (hydroxymethyl) cyclobutyl purines

1989-03-13

1998-03-03

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544243, 544244, 544276, 544314, 544317, 544254, 544265, 560231, A61K 3152, C07D47318, C07D47316, C07D47332

Patent

active

057236097

ABSTRACT:
Antiviral activity is exhibited by compounds having the formula ##STR1## and its pharmaceutically acceptable salts wherein R.sub.1 is ##STR2## wherein R.sub.2 is hydrogen, methyl, fluoro, chloro, bromo, iodo, hydroxy or amino; or trifluoromethyl; R.sub.5 is alkyl; R.sub.6 is hydrogen, alkyl, substituted alkyl, or aryl; and R.sub.7 and R.sub.8 are independently hydrogen, ##STR3##

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