Biomodulators as universal imaging agents

Details Biomodulators as universal imaging agents Biomodulators as universal imaging agents

1991-05-01

1995-03-28

Stoll, Robert L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to cyclopentano-hydrophenanthrene ; derivative thereof

424 165, 424 169, 424 4, 424 9, A61K 4900, A61K 4902, A61K 4904

Patent

active

054014891

ABSTRACT:
Biomodulators, optionally linked to imaging-active moieties, can be administered to a host to enhance images thereof, e.g., NMR-, X-ray- or radio-images, preferably by increasing aberrant tissue signal intensity. Biomodulators can also condition tissue to enhance uptake of otherwise non-specific imaging agents. When linked to drugs, biomodulators can target the same to particular sites in the body.

REFERENCES:
patent: 5021427 (1991-06-01), Elbein et al.
patent: 5047227 (1991-09-01), Rodwell et al.
patent: 5240693 (1993-08-01), Born et al.
patent: 5277892 (1994-01-01), Rhodes
Mann et al., "Cell Surface Oligosaccharide Modulation during Differentiation: IV. Normal and Transformed Cell Growth Control," Mechanisms of Ageing and Development, 44 (1988), pp. 17-33.
Thakur et al., J. Immun. Methods, vol. 152 (1992) pp. 209-216.

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