Process for the preparation of antibiotics

Details Process for the preparation of antibiotics Process for the preparation of antibiotics

1980-10-24

1983-05-31

Lee, Mary C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D48704

Patent

active

043860290

ABSTRACT:
The present invention provides a process for the preparation of a compound of the formula (O): ##STR1## wherein R.degree. is SCH.sub.2 CH.sub.2 NH.sub.2 which process comprises the reaction of a cleavable ester of a compound of the formula (O) wherein R.degree. is H with an optionally protected compound XCH.sub.2 CH.sub.2 NH.sub.2 wherein X is a displaceable group.

REFERENCES:
patent: 4262010 (1981-04-01), Christensen et al.
patent: 4269772 (1981-05-01), Melillo et al.
patent: 4273709 (1981-06-01), Christensen et al.
Methoden Der Organischen Chemie, vol. IX, 103, 114, Georg ThiemeVerlag (1955).
Wagner et al.; Synthetic Organic Chemistry; pp. 787-788 (1953).

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