Substituted 1H-1,2,4-triazoles

Details Substituted 1H-1,2,4-triazoles Substituted 1H-1,2,4-triazoles

1979-08-27

1981-03-31

Rollins, Alton D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424250, 424263, 424269, 544405, 546276, 548269, A61K 3141, A61K 3144, C07D24908, C07D40104

Patent

active

042595045

ABSTRACT:
This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted 1-phenyl-1H-1,2,4-triazoles and/or the pharmacologically acceptable acid-addition salts thereof.

REFERENCES:
patent: 4038405 (1977-07-01), Evans et al.
patent: 4151169 (1979-04-01), Sale et al.
Jackson et al., Chemical Abstracts, vol. 45, columns 6699-6700, (1951).

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