In vitro method of inhibition of HIV using transforming growth f

Details In vitro method of inhibition of HIV using transforming growth f In vitro method of inhibition of HIV using transforming growth f

1988-08-25

1993-08-17

Moezie, F. T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514885, 514931, A61K 3736

Patent

active

052369056

ABSTRACT:
The use of TGF-.beta. to inhibit HIV infection and/or replication is described. Both mature and precursor forms of TGF-.beta. are efficacious in inhibiting production of HIV. The TGF-.beta. used to inhibit HIV may be obtained from natural sources or may be produced by recombinant DNA or chemical synthetic techniques. TGF-.beta.1 and/or TGF-.beta.2 may be used. Additionally, hybrid TGF-.beta.1/.beta.2 molecules may also be utilized.

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