Substituted ureas and processes for their preparation

Details Substituted ureas and processes for their preparation Substituted ureas and processes for their preparation

1979-01-18

1980-12-23

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

424251, 424263, 424272, 424273R, 424274, 546122, 546309, 548163, 548194, 548222, 548233, 544245, 544301, 544329, A61K 31425, C07D27746

Patent

active

042410720

ABSTRACT:
Organic chemical compounds based upon the urea molecule are disclosed which have potent gastric secretion inhibitory properties. The urea is substituted with a heterocyclic ring which may be substituted with one or more loweralkyl groups. The urea is also substituted with loweralkyl and a lower-alkylamino loweralkyl group. The compounds have profound effects on the inhibition of gastric secretions in the gastro-intestinal tract, and compositions for such uses are also disclosed.

REFERENCES:
patent: 2042023 (1936-05-01), Schonhofer et al.
patent: 3404152 (1968-10-01), Thiele et al.
patent: 3864496 (1977-02-01), Diamond et a.
patent: 3896233 (1975-07-01), Brenner et al.
patent: 3897555 (1975-07-01), Loev
Bolhofer et al., Chem. Abstracts, vol. 87, abst. No. 102, 178c (1977).
Burger, Medicinal Chemistry, 2nd Ed., frontispage and pp. 79-81, Interscience Publishers, Inc., NY (1960).

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