Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1988-10-26
1989-08-29
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 13, 530324, 530325, 530326, A61K 3702, C07K 708, C07K 710
Patent
active
048617563
ABSTRACT:
Certain polypeptide-phospholipid complexes consisting of the amphipathic, helical portion of human apo A and its analogs and a phospholipid are useful in the treatment of neonatal respiratory distress syndrome.
REFERENCES:
patent: 4312860 (1982-01-01), Clements
patent: 4338301 (1982-07-01), Tetsuro et al.
R. T. White et al., Nature, 317(26), 361 (1985).
A. Argiolas and J. J. Pisano, J. Biol. Chem., 260(3), 1437 (1985).
Chaffee and Greisheimer, Basic Physiology and Anatomy, J. P. Lippincott Co., New York, 1974, pp. 358-361.
J. B. West, ed., Physiological Basis of Medical Practice, 11th ed., Williams and Wilkins, Baltimore, 1985, pp. 586-592.
Merrell Dow Pharmaceuticals Inc.
Nesbitt Stephen L.
Phillips Delbert R.
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