Spiro-dioxolanes, -dithiolanes and -oxothiolanes, and their use

Details Spiro-dioxolanes, -dithiolanes and -oxothiolanes, and their use Spiro-dioxolanes, -dithiolanes and -oxothiolanes, and their use

1986-01-10

1988-04-05

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 19, 548952, 548409, 540466, 540543, 514409, 514210, 514212, 514184, C07D491113, A61K 31395

Patent

active

047359447

ABSTRACT:
Spiro compounds, comprising a five-membered carbocyclic ring interrupted by two heteroatoms in ring positions 1 and 3 chosen from oxygen and sulfur atoms and in which the carbon atom in ring position 4 is common to a 4 to 8-membered carbocyclic ring interrupted by a nitrogen atom, are useful as pharmaceuticals.

REFERENCES:
Ridley et al., J. Med. Chem. 1969 12, 931.
Rueppel et al., J. Amer. Chem. Soc. 94, 3877 (1972).
Jones et al., J. Chem. Soc. (B) 1973, 6, 1302.
Jones, II et al., J. Chem. Soc., Perkin Trans II, 1973, 4 337.

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