Microfabricated capsules for immunological isolation of cell tra

Details Microfabricated capsules for immunological isolation of cell tra Microfabricated capsules for immunological isolation of cell tra

1994-06-06

1999-04-13

Drodge, Joseph W.

Liquid purification or separation

Filter

Supported, shaped or superimposed formed mediums

21050026, 216 56, 264 4, 424424, 427245, 4283126, 6048911, B01D 6910, A61K 952

Patent

active

058939741

ABSTRACT:
The present invention provides a capsule made of a biologically compatible material with sufficient mechanical strength to form a very thin membrane shell having at least a region with approximately uniformly sized and spaced holes or pores that are large enough to let a desired biologically active molecular product through, while blocking the passage of all larger immunological molecules. The present invention thus provides an immunological isolation of cell transplants contained therein. The present invention also provides a free standing thin film structure that may be used as a component of such a capsule and method for the fabrication of such component and capsules.

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