Substituted imidazo[4,5-b]pyridines and benzimidazoles

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546118, A61K 31435, C07D47104

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active

055278094

ABSTRACT:
Substituted imidazo[4,5-b]pyridines and benzimidazoles are prepared by reacting imidazo[4,5-b]pyridines or benzimidazoles with appropriately substituted benzyl halides. The substituted imidazo[4,5-b]pyridines or benzimidazoles can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.

REFERENCES:
patent: 5128355 (1992-07-01), Carini et al.
patent: 5138069 (1992-08-01), Carini et al.
patent: 5153197 (1992-10-01), Carini et al.
patent: 5155118 (1992-10-01), Carini et al.
patent: 5240938 (1993-08-01), Greenlee
Chemical Abstracts 118:191734 of DE 4200954 published 29 Oct. 1992, 1992.
Chemical Abstracts 118:234063 of EP 513533 published 19 Nov. 1992, 1992.
The Journal of Cell Biology, vol. 50, 1971, pp. 172-186; "The Smooth Muscle Cell", R. Ross.

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