Acridine compounds and methods of combatting viruses with them

Details Acridine compounds and methods of combatting viruses with them Acridine compounds and methods of combatting viruses with them

1978-10-02

1981-01-13

Tovar, Jose

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 80, 544126, 544361, 546103, 546104, 42424856, 424250, A61K 3147, C07D21906

Patent

active

042449545

ABSTRACT:
9-Phenyl(or benzyl)acridines, 9-phenyl(or benzyl)-9-acridinols and acridinium compounds, useful as trypanosomacidal and antibacterial agents, are prepared from aminoalkoxy substituted 9-acridinones via reaction with the appropriate Grignard reagents or aryllithium. The intermediate aminoalkoxy substituted 9-acridinones, prepared from the corresponding halo or hydroxy substituted 9-acridinones, are useful as antiviral agents.

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patent: 2732374 (1956-01-01), Steiger
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patent: 3740403 (1973-06-01), Murdock
Marxer, Helv. Chim. Acta, 49(1), pp. 572-80, (1966), Chemical Abstracts, vol. 64, 12669a.
Albert, "The Acridines," 2nd ed., p. 331, N. Y., St. Martins Press, (1966).

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