Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1982-02-18
1982-10-12
Bond, Robert T.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602393T, 424256, 424273R, C07D51322, C07D47114, C07D47122
Patent
active
043538274
ABSTRACT:
There is provided compounds which exhibit pronounced anticonvulsive and anxiolytic activities of the formula ##STR1## wherein A together with the two carbon atoms denoted as .alpha. and .beta. is the group ##STR2## B is dimethylene, trimethylene or propenylene, R.sup.1 is hydrogen, halogen, trifluoromethyl, amino, nitro, cyano or lower alkyl and R.sup.2 is hydrogen, halogen, trifluoromethyl, amino, nitro, cyano, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulphinyl or lower alkylsulphonyl, and the carbon atom denoted as .gamma. has the (S)--or (R,S)--configuration,
and the pharmaceutically acceptable acid addition salts thereof.
REFERENCES:
patent: 4316832 (1982-02-01), Gerecke et al.
Hunkeler Walter
Kyburz Emilio
Bond Robert T.
Hoffman Frank P.
Hoffmann-La Roche Inc.
Leon Bernard S.
Saxe Jon S.
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