Use of fructose-1,6-diphosphate for treating myocardial infarcti

Details Use of fructose-1,6-diphosphate for treating myocardial infarcti Use of fructose-1,6-diphosphate for treating myocardial infarcti

1982-09-03

1985-10-08

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536117, 435 2, A61K 3166, A61K 3170, C12P 1924

Patent

active

045460957

ABSTRACT:
The invention relates to the treatment of heart disorders. Disruption of heart action or occulision of heart artery results in oxygen deprivation and aerobic metabolism ceases. Unless effective treatment is administered acidosis renders anaerobic metabolism inactive and irreversible tissue damage occurs.
Fructose-1,6-diphosphate is used as a therapeutic agent for treating mammalian subjects experiencing myocardial infection in order to prevent ischemic tissue from irreversible tissue damage.

REFERENCES:
Melloni et al., "Chem. Abst.", vol. 59, 1963, p. 6816(g).
Burreno et al., "Chem. Abst.", vol. 83, 1975, p. 109527(s).
Schuler et al., "Chem. Abst.", vol. 85, 1976, p. 14363(n).
Markov et al., "American Heart Journal", vol. 100, No. 5, Nov. 1980, pp. 639-646.

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