Novel aminonaphthacene derivatives and process for preparation t

Details Novel aminonaphthacene derivatives and process for preparation t Novel aminonaphthacene derivatives and process for preparation t

1984-05-04

1985-10-08

Hollrah, Glennon H.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603511, 2603515, 260365, C07C 1524, C07C 5022, C07C 5036

Patent

active

045459363

ABSTRACT:
An aminonaphthacene derivative of the formula: ##STR1## wherein R.sup.1 is a hydrogen atom, a hydroxyl group or a lower alkoxy group, R.sup.2 is a hydrogen atom or a hydroxyl group, R.sup.3 is a hydrogen atom or a lower alkanoyl group and R.sup.4 and R.sup.5 are, same or different, each a hydrogen atom, a lower alkyl group, a lower hydroxyalkyl group or a group of the formula: ##STR2## wherein A is an alkylene group which may have one or more lower alkyl substituent(s) and R.sup.6 and R.sup.7 are, same or different, each a hydrogen atom, a lower alkyl group, a lower hydroxyalkyl group or a lower aminoalkyl group, and an acid addition salt thereof, which is useful as anti-tumor agent.

REFERENCES:
"The Journal of Medicinal Chemistry", vol. 22, No. 8, pp. 922-926 (1979).
"The Journal of Medicinal Chemistry", vol. 72, No. 11, pp. 1425-1428 (1979).

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