Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1996-06-04
2000-06-06
Marschel, Ardin H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 6, 435 911, 435 912, 536 231, 536 243, 536 2433, 536 253, 536 2532, C12Q 168, C12P 1934, C07H 1900, C07H 2102
Patent
active
060720433
ABSTRACT:
A method for the preparation of optimally fluorescent oligonucleotides wherein fluorescent dye-conjugated nucleotide triphosphates are incorporated into a nucleic acid sequence in a defined repetitive manner which allows for the optimal specific fluorescence of the oligonucleotide. The oligonucleotides of the present invention are useful in the assay of a wide variety of nucleic acid sequences, specifically wherever highly fluorescent nucleic acid probes are desired.
REFERENCES:
patent: 5403708 (1995-04-01), Brennan et al.
patent: 5652099 (1997-07-01), Conrad
New England Biolabs Catalog, (New England Biolab Inc., Beverly, MA), p. 97, 1993.
Marschel Ardin H.
Polyprobe, Inc.
Riley Jezia
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