Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1999-03-22
2000-06-06
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514253, 544405, 544408, A61K 31495, C07D40112, C07D45102, C07D40312
Patent
active
060719001
ABSTRACT:
The present invention relates to therapeutically active azacyclic or azabicyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
REFERENCES:
patent: 4837241 (1989-06-01), Jensen et al.
patent: 4894453 (1990-01-01), Yaso et al.
patent: 5041455 (1991-08-01), Sauerberg et al.
patent: 5082843 (1992-01-01), Cliffe et al.
patent: 5286864 (1994-02-01), Walther et al.
patent: 5328923 (1994-07-01), Sauerberg et al.
patent: 5328924 (1994-07-01), Sauerberg et al.
patent: 5414009 (1995-05-01), Olesen et al.
patent: 5418240 (1995-05-01), Sauerberg et al.
patent: 5508405 (1996-04-01), Walther et al.
patent: 5512574 (1996-04-01), Husbands et al.
patent: 5665745 (1997-09-01), Alt et al.
patent: 5731323 (1998-03-01), Whittamore
Ward et al, J. Med. Chem. 35 pp. 4011-4019, 1992.
Quirion et al, TIPS pp. 80-84, 1989.
Derwent Abstract 43103T-BDE (Feb. 21, 1969).
Derwent Abstract 23326A/13 (May 10, 1976).
Derwent Abstract 21307 D/12 (Apr. 7, 1980).
Derwent Abstract 61811V/35 (Feb. 20, 1973).
Derwent Abstract 18366B/10 (Jul. 27, 1977).
Derwent Abstract 10251B/06 (Jul. 8, 1977).
Derwent Abstract 83-778153/40 Jul. 16, 1982).
Derwent Abstract 83-7653115/38 (Aug. 1, 1981).
Derwent Abstract 85-112228/19 (Oct. 1931).
Derwent Abstract 88-008621/02 (Jun. 30, 1986).
Derwent Abstract 88-256990/36 (Feb. 27, 1987).
Mathew, et al., Am. J. Psychiatry, 137:9, 1118-1120 (1980).
Sim, M. and Houghton, H., J. of Nervous and Mental Disease, 143:6, 484-491 (1966).
Rapaport, et al., Biol. Psychiatry, 29, 658-664 (1991).
Chemical Abstracts, 117:13, p. 766 (Sep. 28, 1992), No. 131387.
Chemical Abstracts, 117:3, p. 702 (Jul. 20, 1992), N. 26428.
Chemical Abstracts, 109:21, p. 712 (Nov. 21, 1988), No. 190381.
Chemical Abstracts, 106:3, p. 601 (Jan. 9, 1987), No. 18488.
Chemical Abstracts, 84:19, p. 482 (May 10, 1976), No. 135479.
Newhouse, et al., Drug Development Research, 38, pp. 278-289 (1996).
Aubert, et al., J. of Neurochemistry, "Comparative Alterations of Nicotinic and Muscarinic Binding Sites in Alzheimer's and Parkinsons's Diseases," pp. 529-541 (1992).
Datzung, B. G., Basic & Clinical Pharmacology, (Appleton & Lange, Norwald), pp. 92-94 (1995).
Merritt Leander
Ward John S.
Bernhardt Emily
Eli Lilly and Company
Stemerick David M.
Vorndran Jones MaCharri R.
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