Process for preparing quinolone and naphthyridone carboxylic aci

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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514312, A61K 3147, C07D21516, C07D21520, C07D21536

Patent

active

061145319

ABSTRACT:
Antibacterial quinolone carboxylic acids and naphthyridone carboxylic acids, having an external amino group attached to their 7-substituent are prepared without the use, and subsequent removal, of blocking groups on the external amino group. In a preferred embodiment, the naphthyridone carboxylic acid is the antibiotic trovafloxacin.

REFERENCES:
Casreact 127:248005, 1997, Glushkov.
Casreact 125:247630, 1995, Palomo.
Casreact 124:343143, Busch, 1996.
Casreact 124:8852, Hommler, 1995.
CA 128:140606, Hawkins, 1998.
CA 126:264093, Allen, 1997.
CA 126:251417, Norris, 1997.
cA 119:117227, Brightly, 1992.

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