Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-08-17
2000-09-05
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514321, 546196, 546197, C07D21162, C07D21160, C07D40106, A61K 31445
Patent
active
061143545
ABSTRACT:
The present invention relates to novel N-substituted azaheterocyclic compounds of the general formula ##STR1## wherein X, Y, Z, R.sup.1, R.sup.2 and r are as defined in the detailed part of the present description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neuragenic pain or inflammation as well as their use for treatment of indications caused by or related to the secretion and circulation of insulin antagonising peptides, e.g. non-insulin-dependent diabetes mellitus (NIDDM) and ageing-associated obesity.
REFERENCES:
patent: 5753678 (1998-05-01), Hohlweg et al.
Andersen Knud Erik
Fischer Erik
Hohlweg Rolf
J.o slashed.rgensen Tine Krogh
Olsen Uffe Bang
Novo Nordisk A S
Rao Deepak R.
Rozek Carol E.
Shah Mukund J.
Zelson Steve T.
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