Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1)

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 711, 435 712, 4352523, 43525411, 4353201, 435325, 435471, 536 231, 536 235, 536 243, 536 2431, 536 245, 530350, C12N 1512, C12N 510, C12N 1563, C07K 14705

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06071722&

ABSTRACT:
AXOR1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing AXOR1 polypeptides and polynucleotides in therapy, and diagnostic assays for such.

REFERENCES:
Cunningham et al. (1989) Science vol. 244, pp. 1081-1085.
George et al. (1988) Macromolecular Sequency & Synthesis ch 12, pp. 127-149, Alan R. Liss Inc.
Hillier et al. (1996) Genome Research, 1996, vol. 6, No. 9, pp. 807-828.
O'Dowd et al. "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes", Gene, vol. 187, pp. 75-81 (1997).
Libert et al "Selective Amplification and Cloning of Four New Members of the G Protein-Coupled Receptor Family", Science, vol. 244, pp. 569-572 (1989).
Copy of PCT International Search Report.
O'Dowd et al., "Discovery of Three Novel G-Protein-Coupled Receptor Genes", Genomics 47, 310-313 (1998).
GenBank Accession No. AF027957. O'Dowd et al. 1998 EMBL GenBank/DDBJ database.
GenBank Accession No. AA883367. NCI-CGAP 1998.
GenBank Accession No. AA332611. Adams et al. 1995, Nature vol. 377, pp. 3-174.

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