Tablets with thioctic acid of specific particle size

Details Tablets with thioctic acid of specific particle size Tablets with thioctic acid of specific particle size

1995-01-05

1996-06-18

Spear, James M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424465, 514951, A61K 920

Patent

active

055275397

ABSTRACT:
The invention relates to a drug formulation in the form of tablets containing thioctic acid (.alpha.-lipoic acid) with an active ingredient content between 45% by weight and 99.9% by weight. The invention is characterized in that 20% to 100% of the active ingredient used has a particle size exceeding 100 .mu.m, particulary between 100 .mu.m and 710 .mu.m, preferably 30% to 80% a particle size between 200 .mu.m and 710 .mu.m.

REFERENCES:
patent: 4678670 (1987-07-01), Tomic
patent: 5118505 (1992-06-01), Koltringer
patent: 5376382 (1994-12-01), Goede et al.

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