Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-06-19
2000-06-06
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
536 243, 436 2, 436149, C12Q 168, C07H 2104, G01N 2700, G01N 33483
Patent
active
060716991
ABSTRACT:
The present invention provides for the selective covalent modification of nucleic acids with redox active moieties such as transition metal complexes. Electron donor and electron acceptor moieties are covalently bound to the ribose-phosphate backbone of a nucleic acid at predetermined positions. The resulting complexes represent a series of new derivatives that are bimolecular templates capable of transferring electrons over very large distances at extremely fast rates. These complexes possess unique structural features which enable the use of an entirely new class of bioconductors and photoactive probes.
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Heller, A., et al
Fraser Scott E.
Kayyem Jon Faiz
Meade Thomas J.
California Institute of Technology
Silva Robin M.
Trecartin Richard F.
Zitomer Stephanie W.
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