Sulfonamide endothelin antagonists

Details Sulfonamide endothelin antagonists Sulfonamide endothelin antagonists

1993-07-15

1995-01-03

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514374, 514376, 514377, 514375, 514379, 514380, 546209, 548243, 548244, 548245, 548246, 548241, C07D26106, A61K 3142

Patent

active

053787153

ABSTRACT:
Compounds of the formula ##STR1## inhibit endothelin, wherein: one of X and Y is N and the other is O; R is naphthyl or naphthyl substituted with R.sup.1, R.sup.2 and R.sup.3 ;

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