Antireproductive tricyclic ortho-fused nitrogen containing compo

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260239BB, 2602455, 2602456, 260325R, 2603261, 424269, 424273R, 546 82, 546 84, 546141, 546143, 548262, 548324, A61K 3147, A61K 3141, C07D47104, C07D48704

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042750660

ABSTRACT:
New tricyclic ortho-fused nitrogen containing compounds of the following formula: ##STR1## wherein R and R.sub.1 are independently selected from hydrogen, fluoro, chloro, bromo and (C.sub.1 -C.sub.4)alkoxy; A may be --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- or --(CH.sub.2).sub.3 --; X represents a nitrogen atom or the group CH; and salts therewith of pharmaceutically acceptable acids.
The compounds possess an outstanding antireproductive utility.

REFERENCES:
patent: 3758480 (1973-09-01), Reimlinger et al.
patent: 3775417 (1973-11-01), De Ruiter et al.
patent: 3895113 (1975-07-01), Sale et al.
patent: 4007276 (1977-02-01), Sale et al.
patent: 4075341 (1978-02-01), Sale et al.
patent: 4075342 (1978-02-01), Sale et al.
patent: 4113731 (1978-09-01), Winters et al.
Grant, J. (Editor), Hackh's Chemical Dictionary, 3rd Edition, McGraw Hill, New York 1944, pp. 74 and 78.

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