Protein kinase C modulators

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514331, 514354, 514357, 546226, 546229, 546231, 546232, 546245, 546246, 546247, A61K 3144, A61K 31445, C07D21106, C07D21160

Patent

active

051890461

ABSTRACT:
PKC modulating compounds of the formula ##STR1## Also disclosed are pharmaceutical compositions including these compounds which inhibit PKC activity, methods of using these compounds to inhibit PKC activity in mammals, and intermediates useful in preparing the PKC modulating compounds.

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patent: 4923863 (1990-05-01), Scopes et al.
Rodger et al. "Homocysteine an atherogenic . . . " CA 112:233248h (1990).

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