Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter
Patent
1990-03-26
1993-02-23
Brown, Johnnie R.
Stock material or miscellaneous articles
Coated or structually defined flake, particle, cell, strand,...
Particulate matter
536 255, 536 256, 424450, 424 89, 514 44, A61K 9127, C07H 2102
Patent
active
051888971
ABSTRACT:
Optically active compounds of the formula ##STR1## wherein n is 1 or 2 and m is 0, 1, 2 or 3 have antiviral activity. Compounds of the formula wherein at least one of the internucleotide phosphorothioate linkages is
REFERENCES:
patent: 4241046 (1980-12-01), Papahadjopoulos et al.
patent: 4565696 (1986-01-01), Heath et al.
patent: 4663161 (1987-05-01), Mannino et al.
patent: 4781871 (1988-11-01), West, III et al.
Devash et al., Science 216:415 (1982).
Eppstein et al., J. Biol. Chem. 257:13390-13397 (1982).
Jager et al., Nucleic Acids Res. Sum. Ser. No. 9:149-152 (1981).
Haugh et al., Eur. J. Biochem. 132:77-84 (1983).
Nelson et al., J. Org. Chem. 49:2314-2317 (1984).
Eppstein et al., J. Biol Chem. 261:5999-60003 (1986).
Eppstein et al., J. Biol. Chem. 261:13873 (1986).
Lee et al., Biochemistry 24:551-555 (1985).
Suhadolnik et al., Prog. Clin. Biol. Res. 202, The 2-5A System: Molecular and Clinical Aspects of the Interferon Regulated Pathway pp. 115-122 (1985).
Kariko et al., Fed. Proc. 46 (6): Abstract 922 (May 1987).
Kariko et al., Nucleosides & Nucleotides 6 (1): 173-184 (1987).
Lehninger, Biochemistry, 2nd Ed. 1978, Worth Publishers, Inc., N.Y., N.Y., p. 315.
Chem. Abst. 108:704923c (1988), abstracting Charubula et al., Nucleosides & Nucleotides 6 (1-2), 513-516 (1987).
Chem. Abst. 105:151228t (1986), abstracting Pauwels et al. Chem. Scr. pl 26(1), 141-5 (1986).
Schryver et al., Prog. Clin. Biol. Res. 202, The 2-5A System: Molecular and Clinical Aspects of the Interferon-Regulated Pathway, pp. 81-88 (1985).
Pfleiderer Wolfgang
Suhadolnik Robert J.
Brown Johnnie R.
Crane L. Eric
Temple University Of The Commonwealth System Of Higher Education
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