Method of preparing a drug delivery system comprising a drug and

Details Method of preparing a drug delivery system comprising a drug and Method of preparing a drug delivery system comprising a drug and

1994-11-21

1997-03-25

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424423, A61K 910, A61K 4736

Patent

active

056142218

ABSTRACT:
This invention relates to a drug delivery system comprising one or more pharmacologically active substances, aggregating agent and a polysaccharide matrix having pseudoplastic properties, to a method for preparing the same, and to the use thereof for providing slow release of the active substance(s) in a biocompatible environment following in vivo injection thereof. The method enables combining of the active substances and the matrix without prior suspending or dissolving the former in an aqueous media. The drug delivery system allows injection of aggregated drugs giving prolonged drug release in a biocompatible environment.

REFERENCES:
patent: Re29066 (1976-12-01), Evans
patent: 4169804 (1979-10-01), Yapel
patent: 4474752 (1984-10-01), Haslam et al.
patent: 4624665 (1986-11-01), Nuwayser

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