Preparation of optically-active isomers of dideoxycarbocyclic nu

Details Preparation of optically-active isomers of dideoxycarbocyclic nu Preparation of optically-active isomers of dideoxycarbocyclic nu

1996-10-10

1998-06-09

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544264, A61K 3152, C07D47340, C07D47316, C07D47330

Patent

active

057636079

ABSTRACT:
A method is provided for preparing an antiviral compound of formula (I): ##STR1## wherein Y is CH, Z is H or NH.sub.2, and X is halo, comprising: (a) reacting a compound of formula (II): ##STR2## with triethylorthoformate, and (b) hydrolyzing the product of said reaction in the presence of acid to yield said compound of formula (I).

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