Methoxy derivatives of 1,4-dithiepino-[2,3-c]-pyrrole

Details Methoxy derivatives of 1,4-dithiepino-[2,3-c]-pyrrole Methoxy derivatives of 1,4-dithiepino-[2,3-c]-pyrrole

1980-03-13

1982-04-27

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544360, 544362, 544363, 544373, 2603265S, A61K 31385, C07D51304

Patent

active

043270956

ABSTRACT:
Compounds of the formula: ##STR1## wherein A represents pyrid-2-yl, quinol-2-yl or 1,8-naphthyridin-2-yl, each such radical being optionally substituted by a halogen atom, or an alkyl or alkoxy radical of 1 through 4 carbon atoms, and R represents hydrogen, an alkyl radical of 1 through 4 carbon atoms, an alkenyl radical of 2 through 4 carbon atoms or an alkanoyl radical of 1 through 4 carbon atoms, are new compounds possessing pharmacological properties. They are particularly active as tranquillizers, anti-convulsants, decontracturants and hypnogenic agents.

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H. R. Schweizer, Helv. Chem. Acta, 52, 2228, (1969).
D. E. Horning, et al., Can. J. Chem. 48, 975-982, (1970).
Tedeshi, et al., J. Pharmacol, 125, 28, (1959).
Swinyard, et al., J. Pharmacol, 106, 319, (1952).
F. Barzachi, et al., Arzneimettel-Forschung, 23, 683, (1973).

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