Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-05-12
1988-12-13
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514370, 514377, 514383, 514397, 514402, 514410, 544322, 544328, 544331, 548181, 548233, 548255, 548266, 548336, 548348, 548422, A61K 31505, A61K 3140, C07D48704
Patent
active
047911131
ABSTRACT:
Mitomycin derivatives having potent antitumor activity having the formula: ##STR1## wherein A is ON--or R.sub.4 N.dbd.N--[wherein R.sub.4 is selected from ##STR2## and optionally substituted heterocyclic groups (wherein R.sub.5 and R.sub.8 are each independently selected from hydrogen, lower alkyl and lower cycloalkyl; R.sub.6 is selected from hydrogen, halogen, hydroxy, lower alkoxy, amino and nitro; R.sub.7 is selected from lower alkyl and lower cycloalkyl; and X is selected from oxygen, sulphur and imino)];
REFERENCES:
patent: 4487769 (1984-12-01), Vyas et al.
Ashizawa Tadashi
Hisamura Koji
Kuroda Tokuyuki
Morimoto Makoto
Ohsawa Yutaka
Daus Donald G.
Kyowa Hakko Kogyo Kabushiki Kaisha
Teoli, Jr. William A.
LandOfFree
Mitomycin derivatives as antileukemia agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mitomycin derivatives as antileukemia agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mitomycin derivatives as antileukemia agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2196376