Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-09-12
1986-03-11
Rollins, Alton D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
2602455, 260239B, 260239BF, 2603303, 514293, 546 83, 546114, A61K 3144, A61K 3155, C07D51314
Patent
active
045755043
ABSTRACT:
Compounds of the formula ##STR1## wherein A is ##STR2## and R is hydrogen, alkyl of 1 to 5 carbon atoms, alkanoyl of 1 to 5 carbon atoms, alkenyl of 3 to 5 carbon atoms, (alkoxy of 1 to 4 carbon atoms)carbonyl, or aralkyl of 7 to 11 carbon atoms optionally halo-substituted,
and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs.
REFERENCES:
patent: 3882125 (1975-05-01), Dohmori et al.
patent: 4220776 (1980-09-01), Whitney et al.
patent: 4244952 (1981-01-01), Munakata et al.
patent: 4275065 (1981-06-01), Wei et al.
patent: 4414225 (1983-11-01), Sauter et al.
Taurins et al., Can. J. Chem., vol. 49, pp. 4054-4064 (1971).
Grell Wolfgang
Griss, deceased Gerhart
Hurnaus Rudolf
Kobinger Walter
Pichler Ludwig
Dr. Karl Thomae GmbH
Rollins Alton D.
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