Sulfated glycosaminoglycanoid derivatives of the heparin and hep

Details Sulfated glycosaminoglycanoid derivatives of the heparin and hep Sulfated glycosaminoglycanoid derivatives of the heparin and hep

Filed on

1994-10-19

Date issued

1996-08-06

Examiner

Robinson, Douglas W.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Designated organic active ingredient containing

SubSubClass

Carbohydrate doai

Other Related Categories

514 56, 514 61, 536 21, 536118, 536122, A61K 31715, A61K 31725, C08B 3710, C07H 510

Type

Patent

Status

active

Patent number

055434037

Description

ABSTRACT:
The invention relates to sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type, of which N-sulfate, N-acetate, and hydroxy groups, are replaced by alkoxy, aryloxy, aralkoxy, or O-sulfate groups. The compounds have antithrombotic and smooth muscle cell proliferation inhibiting activities.

REFERENCES:
patent: 3301848 (1967-01-01), Halleck
patent: 4105760 (1978-08-01), Szejtli et al.
patent: 4221907 (1980-09-01), Nair et al.
patent: 4699900 (1987-10-01), Bayol et al.
patent: 4713373 (1987-12-01), Bayol et al.
patent: 4818816 (1989-04-01), Petitou et al.
patent: 4841041 (1989-06-01), Van Boeckel et al.
patent: 5380716 (1995-01-01), Conrad et al.

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