Substituted alicyclic amine-containing macrocyclic immunomodulat

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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C07D49812, A61K 3133

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active

055301193

ABSTRACT:
Compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein one of R.sup.104 and R.sup.105 is hydrogen, and the other of R.sup.104 and R.sup.105 is a group having the formula ##STR2## as well as pharmaceutically compositions containing such compounds and methods of immunomodulative therapy utilizing the same.

REFERENCES:
patent: 4894366 (1990-01-01), Okuhara et al.
patent: 5208228 (1993-05-01), Ok et al.
patent: 5208241 (1993-05-01), Ok et al.
patent: 5262533 (1993-11-01), Sinclair et al.

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