Cyclohexadiene derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514345, 514349, 514519, 514524, 514523, 546286, 546292, 546293, 546296, 546297, 546307, 546304, 546329, 546345, 546350, 558404, 558408, 558409, 560 47, 560 18, 560 10, 560 21, 560 48, 562426, 562433, 562435, A61K 3144, A61K 31275, C07D21384, C07C22934

Patent

active

055300146

ABSTRACT:
The cyclohexadiene derivatives are prepared by reaction of cyclohexanones with amines and subsequent dehydration. The compounds are suitable as active compounds in medicaments on account of their property of being selective modulators of calcium channel-dependent potassium channels.

REFERENCES:
K. Take, et al., Chem. Pharm. Bull., vol. 39, No. 11, pp. 2915-2923, (1991).
T. J. O'Dell, et al., Neuroscience Letters, vol. 94, pp.93-98, (1988).

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