Process for preparing 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)ni

Details Process for preparing 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)ni Process for preparing 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)ni

1981-09-17

1982-08-31

Milestone, Norma S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546250, C07D21385

Patent

active

043473636

ABSTRACT:
A process for preparing cardiotonically active 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)nicotinonitriles which comprises reacting a pyridinylmethyl methyl ketone with ethoxymethylenemalononitrile, where pyridinyl is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower-alkyl substituents.

REFERENCES:
patent: 4223149 (1980-09-01), Opalka, Jr. et al.
patent: 4276293 (1981-06-01), Lesher et al.

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