Parenteral water-miscible non intensely colored injectable compo

Details Parenteral water-miscible non intensely colored injectable compo Parenteral water-miscible non intensely colored injectable compo

1998-07-21

2000-12-12

Lee, Howard C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

424 7805, 424449, A61K 3118

Patent

active

061600199

ABSTRACT:
A Parenteral Water-miscible non-intensely colored injectable composition of Non-steroidal anti-inflammatory drugs is disclosed. The invention utilizes solubilization techniques to achieve sufficiently high concentrations of Nimesulide suitable to deliver therapeutic doses in conveniently small volumes using water and without any salt form or complexing agent of Nimesulide. In the composition of the invention all the ingredients of the base are hydrophillic. The hydrophillic base serves the advantage of better miscibility with body fluids, faster drug disposition and better compatibility with the tissue environment.

REFERENCES:
patent: 5688829 (1997-11-01), Jain et al.
patent: 5716609 (1998-02-01), Jain et al.
Daffonchio.L et al. Inflammatory Research 45: 259-264, 1995.

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