Process and intermediates for preparing azabicyclo[2.2.2]octan-3

Details Process and intermediates for preparing azabicyclo[2.2.2]octan-3 Process and intermediates for preparing azabicyclo[2.2.2]octan-3

1993-01-19

1995-08-15

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D45302

Patent

active

054420687

ABSTRACT:
Azabicyclo [2.2.2.]octan-3-imines of the general formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are as defined herein are prepared by reacting a compound of the formula ##STR2## with a compound of the formula ##STR3## wherein A is MgCl, MgBr or Li.

REFERENCES:
Morrison & Boyd, Organic Chemistry, 3rd Ed, pp. 179 & 632.
Urbach et al, Tetrahedron Letters, 25, 1143-6 (1984).
King, Tetrahedron Letters, 24, 3281-2 (1983).

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