Molecular cloning of antigens shared by rat- and human-derived P

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4353201, C07H 2104, C12N 1579

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054420504

ABSTRACT:
DNAs encoding antigens of mammalian, Pneumocystis carinii including the gp116 major surface antigen of rat and human P. carinii; P. carinii DNA containing homologous nucleotide sequences to the antigen encoding DNA; RNAs, proteins, monospecific antibodies and chimeric molecules derived from the DNAs; and probes and diagnostic methods, vaccine compositions and anti-P. carinii agents, and methods of treatment for and prophylaxis against P. carinii infection and pneumonitis are claimed.

REFERENCES:
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