Arylalkyl and aryloxyalkyl phosphonates as antiviral agents

Details Arylalkyl and aryloxyalkyl phosphonates as antiviral agents Arylalkyl and aryloxyalkyl phosphonates as antiviral agents

1979-04-05

1980-08-12

Sutto, Anton H.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

260403, 260946, A61K 3166, C07F 940

Patent

active

042173469

ABSTRACT:
Arylalkyl and aryloxyalkylphosphonates, useful as antiviral agents, are prepared by reacting an arylalkyl or aryloxyalkyl halide with a trialkyl phosphite, or with an alkali metal salt of a dialkyl phosphonate, trialkyl phosphonoalkanoate or dialkyl phosphonoalkanone.

REFERENCES:
patent: 3917718 (1975-11-01), Collins
patent: 4031246 (1977-06-01), Collins et al.
patent: 4045468 (1977-08-01), Kurono et al.
Baron et al., "Annual Reports in Medicinal Chemistry", vol. 10 (1975), Chapter on Antiviral Agents, p. 166.
Linn et al., "J. Am. Chem. Soc.", vol. 87, (1965), pp. 3657-3672.

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