Heterocyclic iminobismethylenebisphosphonic acid derivatives

Details Heterocyclic iminobismethylenebisphosphonic acid derivatives Heterocyclic iminobismethylenebisphosphonic acid derivatives

1994-04-13

1995-08-15

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514 89, 514 94, 546 22, 546 23, 548112, 548113, 548119, A61K 31675, C07F 906, C07F 928

Patent

active

054419450

ABSTRACT:
The heterocyclic iminobismethylenebisphosphonic acid derivatives of the general formula (I) ##STR1## wherein n is an integer of 0-5 and the group of the formula ##STR2## represents a 4-7 membered monocyclic or 7-11 membered condensed heterocyclic ring group which may be substituted by a halogen atom or a lower alkyl group and contains 1-2 nitrogen atoms their esters and salts thereof are described. The said compounds are useful as a bone resorption inhibitor, a dental calculus formation inhibitory agent or a polyvalent metal ion complex salt forming agent.

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English language abstract of FR 2185387.
English language abstract of JP 59-52805.

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