Antagonists of gonadotropin releasing hormone

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514326, 514327, 514330, 514331, 514415, 514419, 514422, 514423, 514428, 514538, 514542, 514601, 514605, 514613, 514616, 514619, 514621, 514784, 514785, 546200, 546201, 546208, 546216, 546226, 546227, 546229, 546232, 546233, 546238, 546245, 546248, 548453, 548455, 548494, 548504, 548518, 548523, 548524, 548530, 560 19, 562433, 562443, 564 98, 564 99, 564123, 564163, 564169, 564180, A61K 31405, A61K 31454, A61P 1508, C07D21126, C07D40114

Patent

active

061599891

ABSTRACT:
There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.

REFERENCES:
patent: 4252803 (1981-02-01), Webb
patent: 5756507 (1998-05-01), Goulet et al.
patent: 5780437 (1998-07-01), Goulet et al.
patent: 5849764 (1998-12-01), Goulet et al.
Ulrich Cirkel, "Medical treatment of symptomatic endometriosis," Human Reproduction, vol. 11, Suppl. 3, pp. 89-101, 1996.
P. Michael Conn et al., "Gonadotropin-Releasing Hormone and Its Analogs," Ann. Rev. Med., vol. 45, pp. 391-405, 1994.
Gary Hodgen, "GnRH agonists and antagonists in ovarian stimulation," Human Reproduction, vol. 11, Suppl. 1, pp. 123-132, 1996.
M. Filicori et al., "GnRH Agonists and Antagonists," Drugs, vol. 35, pp. 63-82, 1988.
Robert L. Barbieri, "Clinical Applications of GnRH and Its Analogs," TEM, vol. 3, No. 1, pp. 30-34, 1992.
Randall A. Loy, "The pharmacology and the potential applications of GnRH antagonists," Current Opinion in Obstet. & Gyno., vol. 6, pp. 262-268, 1994.
Anand S. Dutta, "Luteinizing Hormone-Releasing Hormone (LHRH) Antagonists," Drugs of the Future, vol. 13, No. 8, pp. 761-787, 1996.
Annu. Rev. Med., vol. 45, pp. 391-405 (1994), by P. M. Conn, et al.
Drugs of the Future, vol. 13, No. 8, pp. 761-787 (1988), by A. Dutta.
Current Opinion in Obstet. & Gyno., vol. 6, pp. 262-268 (1994), by R. Loy.
TEM, vol. 3, No. 1, pp. 30-34 (1992), by R. Barbieri.
Drugs, vol. 35, pp. 63-82 (1988), by M. Filicori, et al.
Human Reproduction, vol. 11, Suppl. 3, pp. 89-101 (1996), by U. Cirkel.
Human Reproduction, vol. 11, Suppl. 1, pp. 123-132 (1996), by G. Hodgen.

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