Method and composition for treatment of inflammatory bowel disea

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514279, 514300, 514359, 514365, 514367, 514408, 514423, 548146, 548152, 548200, 548201, 548400, 548452, 548469, 560312, 562623, C07D20900, C07D27504

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active

061599832

ABSTRACT:
A composition in unit dosage form for the inhibition, prevention or treatment of inflammatory bowel disease comprising an effective amount of a compound having the formula: ##STR1## and a pharmaceutically acceptable carrier therefor. Also disclosed is a method for the inhibition, prevention or treatment of inflammatory bowel disease comprising administering to a human or non-human mammal in need thereof an effective amount of a compound having the formula: ##STR2##

REFERENCES:
patent: 5322961 (1994-06-01), Bergeron, Jr.
patent: 5367113 (1994-11-01), Bergeron, Jr.
patent: 5840739 (1998-11-01), Bergeron et al.
Kato, et al., "Synthesis and Antihypertensive Activity of 5-(2-hydroxyphenyl)-1-3-mercaptopropionyl)-2-pyrrolidinecarboxylic Acids" Chem. Pharm. Bull., 1985, 33(11), 4836-46.
Bergereon, et al., "The Desferrithiocin Pharmacophore" J. Med. Chem., 1994, 37, 1411-17.

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