Preparation of substituted (dichloromethyl)pyridines

Details Preparation of substituted (dichloromethyl)pyridines Preparation of substituted (dichloromethyl)pyridines

1986-04-23

1988-04-19

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546286, 546288, 546289, 546295, 546297, 546304, 546306, C07D21326, C07D21332

Patent

active

047390700

ABSTRACT:
2- and 4-(Dichloromethyl)pyridines containing electron withdrawing substituents on the ring are prepared by the reaction of the corresponding 2- or 4-halopyridines with excess chloroform in the presence of a strong base in a medium containing a dipolar aprotic solvent or a phase transfer catalyst. 3-Chloro-5-(trifluoromethyl)-2-(dichloromethyl)pyridine, for example, is prepared by the reaction of 2,3-dichloro-5-(trifluoromethyl)pyridine with chloroform in the presence of sodium hydroxide and N-methylpyrrolidone. Substituted 2-(dichloromethyl)pyridines are useful as agricultural pesticides and as intermediates for the preparation of agricultural pesticides.

REFERENCES:
patent: 4172203 (1979-10-01), Ison
patent: 4260766 (1981-04-01), Morris
patent: 4499276 (1985-02-01), Malhotra et al.
patent: 4499277 (1985-02-01), Malhotra et al.

Affiliated with

Also associated with

Rating

Preparation of substituted (dichloromethyl)pyridines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of substituted (dichloromethyl)pyridines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of substituted (dichloromethyl)pyridines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2176295