Process for the preparation of thienamycin and intermediates

Details Process for the preparation of thienamycin and intermediates Process for the preparation of thienamycin and intermediates

1985-07-12

1988-04-19

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540310, 514210, 260239A, C07D48704, A61K 3140

Patent

active

047390484

ABSTRACT:
Disclosed is a process for the total synthesis of thienamycin from L-aspartic acid via intermediate III: ##STR1##

REFERENCES:
patent: 3992377 (1976-11-01), Chauvette
patent: 4123528 (1978-10-01), Cama et al.
patent: 4256739 (1981-03-01), Woodward
patent: 4310538 (1982-01-01), Christensen et al.
patent: 4318912 (1982-03-01), Christensen et al.
Scartazzini et al., Helvetica Chimica Acta, 58(8), 1975, pp. 2437-2450.

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