Process for preparing trans-piperidine-2,5-dicarboxylates

Details Process for preparing trans-piperidine-2,5-dicarboxylates Process for preparing trans-piperidine-2,5-dicarboxylates

1994-03-24

1996-02-06

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21160

Patent

active

054896886

ABSTRACT:
Process for the preparation of a dialkyl trans-piperidine-2,5-dicarboxylate from a corresponding dialkyl cis-piperidine-2,5-dicarboxylate via a trans-substituted pyridine derivative of the formula ##STR1## wherein R is a (C.sub.1 -C.sub.3)alkyl group.

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Mastafanova et al., Chem. Heterocyclic Compounds, Translated from Russian, v. 21, pp. 305-309 (1985).
J. Am. Chem. Soc., v. 97, No. 1, 159-167 (1975).
Chem. Abstr., v. 103, No. 23, 1985, Mastafanova et al., Abst. No. 195965u.
Chem. Abstr., v. 107, No. 7, 1987, Kuleshova et al., Abstr, No. 58343h.
Prestridge et al., J. Org. Chem., V. 40 (22), 3287, (1987).
Albert et al., Synthesis, 635, 1987.

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