Photolabile nucleoside and peptide protecting groups

Details Photolabile nucleoside and peptide protecting groups Photolabile nucleoside and peptide protecting groups

1995-02-16

1996-02-06

Jones, W. Gary

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, C07H 2100, C07H 2102, C07H 2104

Patent

active

054896789

ABSTRACT:
A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protective groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.

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