Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-04-28
1988-04-19
Milestone, Norma S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549292, 514824, 560256, 424 79, A61K 31365, C07D30930
Patent
active
047389826
ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) or (II): ##STR1## and pharmaceutically acceptable salts thereof the compounds of the formula (II) in which R is hydrogen are disclosed.
REFERENCES:
patent: 4231938 (1980-11-01), Monaghan et al.
Arison Byron H.
Greenspan Michael D.
Yudkovitz Joel B.
DiPrima Joseph F.
Merck & Co. , Inc.
Milestone Norma S.
Sudol, Jr. Michael C.
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