Pyridine derivatives, and use as anti-ulcer agents

Details Pyridine derivatives, and use as anti-ulcer agents Pyridine derivatives, and use as anti-ulcer agents

1986-06-18

1988-04-19

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546271, A61K 31415, C07D40106, C07D40112

Patent

active

047389753

ABSTRACT:
The compound of the formula ##STR1## wherein R.sup.1 is hydrogen, fluorine, methoxy or trifluoromethyl, R.sup.2 is a C.sub.1-8 alkyl, R.sup.3 is a C.sub.1-8 alkyl which may be fluorinated, and n is 0 or 1, or a pharmacologically acceptable salt thereof is useful for prevention and treatment of digestive ulcers (e.g. gastric ulcer, duodenal ulcer) and gastritis.

REFERENCES:
patent: 4045563 (1977-08-01), Berntsson et al.
patent: 4255431 (1981-03-01), Junggren et al.
patent: 4472409 (1984-09-01), Senn-Bilfinger
European Patent Publication Nos. 166,287 and 167,943, (Basic Abstracts Journal).
Australian Patent Publication No. 8,435,643, (Basic Abs. Journal).

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