Cough/cold mixtures comprising non-steroidal anti-inflammatory d

Details Cough/cold mixtures comprising non-steroidal anti-inflammatory d Cough/cold mixtures comprising non-steroidal anti-inflammatory d

1986-07-21

1988-04-19

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514290, 514325, 514568, A61U 3119, A61U 3144, A61U 31435, A61U 31445

Patent

active

047389664

ABSTRACT:
Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an antihistamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.

REFERENCES:
Cioli et al, "A Toxicological and Pharmacological Study of Ibuprofen Guaiacol Ester (AF 2259) in the Rat", Toxicology and Applied Pharmacology, vol. 54, pp. 332-339 (1980).
Catanese et al, "Studies on the Oral Absorption of Ibuprofen Guaiacol-Ester in Man", Boll. Chim. Farm., vol. 121, pp. 567-572 (1982).
Barillari et al, "A Study of the Absorption and Tolerance of Ibuprofen Guaiacol Ester in Man After Repeated Oral Administration", Boll. Chim. Farm., vol. 121, pp. 626-631 (1982).
Catanese et al, "A Study of the Serum Concentrations of Ibuprofen and Guaiacol in Rats After Oral Administration of Ibuprofen, Guaiacol and AF 2259", Boll. Chim. Farm., vol. 118, pp. 232-238 (1979).

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