Pharmaceutical compositions

Details Pharmaceutical compositions Pharmaceutical compositions

1979-10-02

1981-11-24

Sneed, Helen M. S.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Anti-idiotypic

423409, 260429R, A01N 1100, C01F 1500

Patent

active

043024467

ABSTRACT:
A stable, microcrystalline form of cisplatin, a process for its preparation, and stable, sterile dry-mix formulations thereof which are more rapidly reconstituted with sterile water to produce solutions suitable for intravenous administration to man than are similar formulations containing "regular" cisplatin. The microcrystalline cisplatin and dry-mix formulations thereof are prepared without the use of lyophilization.

REFERENCES:
Greene et al., American Journal of Hospital Pharmacy 36, 38-43, (1979).
Rozencweig et al., Annals of Internal Medicine, 86, 803-812, (1977).
Talley et al., Cancer Chemotherapy Reports, 57, 465-471, (1973).
Rossof et al., Cancer, 30 1451-1456, (1972).
Rosenberg et al., Nature 205 698-699, (1965).
Rosenberg et al., Nature 222 385-386, (1966).
Handelsman et al., Clinical Brochure, Cis Platinum (II), Diamminedichlori de National Cancer Inst., pp. 31 & 32, (1974).

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